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one that's too acidic may sting or cause sensitivity

Triple mutation of Cys26, Trp35, and Cys126 in stromal ascorbate peroxidase confers H2O2 tolerance comparable to that of the cytosolic isoform

Additionally, the increased MDA levels observed upon SYNCRIP depletion were significantly reduced following SYNCRIP restoration (Figure 3E-G), further linking SYNCRIP function to suppression of ferroptosis

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The goal is not aggressive injury but controlled stimulation