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The researchers also found that the mean weight loss between groups was significantly different, with those who had BMS having a 31.1 percent weight reduction and those taking GLP-1s having only a 12.9 percent reduction

Not to get too deep into the science, but a PPAR agonist delivered selectively because of GLP1 and GIP receptors may mean that we can see the insulin sensitizing benefit of this drug class without the negative side effects that prior meds in this class have suffered from

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Upregulates collagen, elastin, and glycosaminoglycan synthesis

Though this data is encouraging, human research is needed

This GLP-1 plateau playbook is a clinic grade troubleshooting workflow for weight loss practices and telehealth programs when patients feel stuck and motivation drops