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The Synergy Hypothesis Bowers et al
Working and Storage
The majority of the population meets the recommended daily allowance of 0.9-1.3 mg/day.[ref] People more likely to suffer from riboflavin deficiency include: The elderly, women on birth control, vegans, and alcoholics are more likely to have a deficiency.[ref] People who exercise a lot are at a risk of deficiency if their intake isnt increased to meet the energy demand.[ref] Mothers who are breastfeeding may need more riboflavin because breast milk contains a lot of riboflavin and FAD.[ref] The need for riboflavin increases significantly in pregnancy.[ref] However, there is a difference between not having a severe deficiency and getting what is optimal for your specific needs , taking into account genetics and lifestyle
A 2025 review confirmed that potent GLP-1 RAs are associated with significant gastrointestinal issues including nausea, vomiting, and diarrhea (PubMed)
Most studies that have looked into this have been focused on the birth control pill, but its good to be cautious even if youre using other hormonal contraceptives since there isnt much research about how they may be affected by this supplement
