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The temporal distribution of publications, shown in Figure 3, reveals a clear upward trend in research activity over time

Age-related changes in the extracellular matrix of nucleus pulposus and anulus fibrosus of human intervertebral disc

For research protocols at higher risk for hypoglycemia, more precautions may be warranted

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Several studies have demonstrated the potential of probiotics in cancer prevention through various mechanisms including modification of microbiota, neutralization of carcinogens, vitamin and short-chain fatty acids synthesis, improved gut barrier function, inhibition of cell proliferation, cell apoptosis, and anti-inflammatory and anti-pathogenic activity with effects on lowering tumor growth and metastasis

Each pen contains one dose, and each dose is used in its entirety