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5.3.2 Endometrial receptivity Endometrial receptivity refers to the temporary state in which the endometrium possesses the capacity to support embryo positioning, adhesion, penetration, and implantation

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Since it does not require the action of dihydrofolate reductase for its conversion, its function as a vitamin is unaffected by inhibition of this enzyme by drugs such as methotrexate

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9.3 Comparative clinical efficacy and target populations Clinical evidence indicates that Rhodiola rosea produces modest but reproducible antidepressant effects in mild to moderate depression, with dose-dependent efficacy and favorable tolerability compared to SSRIs