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For patients who are deficient in B12 or borderline low, correcting that deficiency may help improve fatigue, sluggishness, or weakness

Masui 58(1):5158 [PubMed] [Google Scholar] Vahl N, Moller N, Lauritzen T, Christiansen JS, Jorgensen JO (1997) Metabolic effects and pharmacokinetics of a growth hormone pulse in healthy adults: relation to age, sex, and body composition

51 , 3641, 3.0.CO;2-T (1997)

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Under high uracil misincorporation as occurs in severe folate deficiency or marked MTHFR impairment BER creates double-strand breaks when two abasic sites on opposite strands are cleaved in close proximity before repair is completed