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These results will reassure patients and physicians caring for them, and support doctors in choosing the most appropriate drug without consideration of possible differences in the risk of retinopathy complications. This article was developed by the editorial staff in conjunction with experts in the field

A cyclic lactam bridge forms between Asp and Lys residues

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For the annulus fibrosus (the outer ring of the disc made primarily of collagen), this mechanism may support healing of small tears and prevent further deterioration

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