Conversely, in lung and breast cancer, elevated CHAC2 correlates with advanced tumor stage and grade, indicating a worse prognosis (Liu et al., 2017
Those most vulnerable to B12 deficiencies include vegans, older adults, individuals with gastrointestinal absorption problems, and those whove had weight-loss surgery
Chem Pharm Bull
The injections range in frequency and strength, depending on your condition
In one case study, a 5 month old breastfed infant of a vegan mother (who actually received a prenatal vitamin containing 96% of her daily needs of B12 throughout her pregnancy) presented with many of the above symptoms and required a 19 day hospital stay to stabilize
My recommended gut healing protocols are as follows: Remove inflammatory triggers: Gluten, processed seed oils, excess alcohol, NSAIDs Support gut barrier function: L-glutamine (5-20g daily), zinc carnosine (75-150mg twice daily), collagen peptides Optimize the microbiome: High-quality probiotics, fermented foods, prebiotic fiber Address underlying infections: SIBO, candida overgrowth, and parasites if they are present This may take a few months, but the payoff extends far beyond reducing peptide site reactions