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Pretreatment with intravenous CoQ10 (5 mg/kg) reduced serum ALT and markers of oxidative stress, but had no effect on liver glutathione levels (Amimoto 1995)

The idea that a lipid-rich substance has the potential to reverse the effects of certain drugs began in the 1960s, when several animal experiments demonstrated that intravenous administration of an oil emulsion decreased the duration of action of thiopental or decreased the free fraction of chlorpromazine in blood

This product is not intended for human or animal use , including ingestion, injection, inhalation, topical application, or any form of administration

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Indeed, when the effect of 2APB on drug metabolism was evaluated, it was discovered that 2APB is a P450 inhibitor as directly shown in vitro and observed in vivo when the protection correlated with inhibition of protein adduct formation [155]