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Numerous investigations have demonstrated that peroxisomes facilitate the occurrence of ferroptosis through the production of polyunsaturated ether phospholipids (PUFA-ePLs), which serve as substrates for lipid peroxidation and ultimately lead to ferroptosis (Zou et al., 2020b)

The Woodlands, TX: Lexicon Pharmaceuticals, Inc

The pls Package: principal component and partial least squares regression in R

Pirard-Franchimont C, Pirard GE

Vasques-Monteiro IML, Silva-Veiga FM, Miranda CS, de Andra Gonalves CB, Daleprane JB, Souza-Mello V

This means the comparison slightly favors tirzepatide, though all three tirzepatide doses still showed statistically significant advantages