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J Clin Psychiatry (1982) 43:388384

Eur J Neurosci (2004) 20(4):10518

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But when we look at the literature in patients with PCOS we see an interesting story, serum testosterone seems to decrease when GLP1 inhibitors are taken alone (10) and when they are taken with metformin there is an increase in SHBG (11,12.) This seems to me to again point to how complex the endocrine system is: we dont fully understand the interplay between insulin, sex steroid hormones, and SHBG