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This would decrease circulating levels of estrogen, gonadotropin-releasing hormone (GnRH), prolactin, and gonadotropins and the ability of melatonin to modulate the activity of enzymes involved in the synthesis of estrogens, both gonadal and extragonadal

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[DOI] [PMC free article] [PubMed] [Google Scholar] 4.Thyroid hormone excess and glucose intolerance

This phenomenon raises important questions about the quality and composition of weight loss, as retaining lean body mass is essential for maintaining overall strength, mobility, and metabolic health

[DOI] [PMC free article] [PubMed] [Google Scholar] 51.Snetselaar L.G., de Jesus J.M., DeSilva D.M., Stoody E.E