Skimping on protein can lead to muscle loss, which is why the recommendation is to consume 1 to 1.5 grams of protein per kilogram of weight per day if you take a GLP-1 medication
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These consultations allow monitoring of: Glycaemic control through HbA1c measurements (usually every 36 months) Weight changes and body composition Tolerability and adverse effects , particularly gastrointestinal symptoms Blood pressure and heart rate Renal function tests NICE recommends (NG28) that GLP-1 therapy should be continued only if there is demonstrable benefittypically defined as an HbA1c reduction of at least 11 mmol/mol (1.0%) and weight loss of at least 3% of initial body weight at six months for diabetes indications
Identifying GLP-1 as a biologically active hormone involved multiple scientists in the 1980s: Joel Habener, Svetlana Mojsov, Daniel Drucker, and Jens Juul Holst, working across U.S
the Phase 3 confirmatory publications are what would elevate that tier