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The glutathione moieties of GSSR and GSH have to interact with different protein areas as a result of the S N 2 geometry of both half-reactions of the ping pong bi-bi mechanism (Fig

EGLN1/c-Myc induced lymphoid-specific helicase inhibits ferroptosis through lipid metabolic gene expression changes

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[DOI] [PMC free article] [PubMed] 143.Tong LC, Wang Y, Wang ZB, Liu WY, Sun S, Li L, et al

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Among them, tryptophan metabolic bacteria such as Lactobacillus decreased, resulting in a decrease in the activity of diamine 2,3-dioxygenase (IDO) and tryptophan metabolites such as indo-3-lactate can inhibit Th 17 differentiation and promote Treg function via the aromatic hydrocarbon receptor (Zelante et al., 2013