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Why does this article warn against choosing purely on price

What theyre saying: We believe that inhibiting new pathways on top of GLP-1 receptor agonism has the potential to achieve comparable overall reductions in body weight, but with improved quality of a weight loss, resulting in more fat loss while preserving or actually increasing muscle mass. Regenerons CSO George Yancopoulos The big picture If any of these medications (or combinations of medications) can actually enable people to lose weight while preserving muscle mass, the impact on public health could be huge but itll likely be years before they reach the market

But even with pharmaceutical assistance, the set point defense eventually creates enough counterforce to slow or stop weight loss temporarily

It is the single most important number in the entire dosing process

10.1016/S2468-1253(23)00068-7 48 LuX.XuC.DongJ.ZuoS.ZhangH.JiangC.et al (2021)