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First, the above four cell lines were inoculated in a confocal culture dish at a density of 1 10 5 per well and cultured in incubators (37, 5% CO 2 ) for 24 h

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The enzyme 5-methyltetrahydrofolate-homocysteine methyltransferase (MTR) attaches a methyl group from methylcobalamin (b12) to homocysteine resulting in methionine