dihexa human safety data Evaluation of Metabolically Stabilized Angiotensin IV Analogs as Procognitive/Antidementia Agents DIHEXA | Peptide Synthetic |

10.1002/path.2277 153 XueX

While LPS exposure alone resulted in a 59% increase in oxidized DCF (a measure of ROS) compared to control cells, pretreatment with GHK-Cu at concentrations of 1, 5, and 10 M significantly decreased ROS production

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This upregulated gene expression could suggest that P-15 promotes osteoblastic activity in human osteoblast cells