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Serious reactions are extremely uncommon

10.1124/jpet.110.173948 [DOI] [PubMed] [Google Scholar] Kieffer B

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NRF2 functions as a central transcriptional regulator that induces cytoprotective genes such as SLC7A11 and GPX4, thereby counteracting oxidative stress in cognitive impairment (Yang et al., 2024)

Thus, we investigated the expression of mitophagy-related proteins using western blot analysis and found that KU-57788 significantly increased the levels of p62, LC3B, Pink1 and Beclin1, and decrease the level of Parkin and BNIP3 in ATC cells (Fig