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Upon binding to insulin receptors, this hormone triggers glucose uptake by cells and regulates metabolic processes
Given the time frame of symptom onset of 8.5 weeks after initiation of statin therapy and normalization of aminotransferases after only medication cessation without additional therapy, it is conceivable that the cholestatic liver injury was secondary to atorvastatin use
Activation of adenosine A 2A receptor reduces osteoclast formation via PKA- and ERK1/2-mediated suppression of NFB nuclear translocation
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KN has received honoraria from AstraZeneca, Bayer, Boehringer Ingelheim Japan, Daiichi Sankyo, Eli Lilly Japan, Kowa, Mitsubishi Tanabe, MSD, Novartis, Novo Nordisk, and Otsuka
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