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Caffeine patches are marketed as an alternative to coffee and other forms of ingested caffeine, but just how good are these patches

Riffault B, Kourdougli N, Dumon C, Ferrand N, Buhler E, Schaller F, et al

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Long-term safety data The most compelling safety evidence comes from a 15-year follow-up study on long-term epithalamin treatment

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If the vitamin is administered by injection in response to a deficiency and enters the bloodstream directly in high concentrations, an immunologic reaction with skin reactions is possible