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Long-term data and effectiveness of driving down chronic conditions using GLP-1s will be interesting to say the least

However, when paired with potent GLP-1 and GIP agonism, the glucose-raising effect of glucagon is overridden by the insulinotropic effects of the other two pathways

It peaks 1 to 3 hours after injection, can persist at lower levels for 12 to 24 hours, and typically resolves within 48 hours

There is no question that dietary optimization and the use of better studied supplements like omega-3s or probiotics are likely to be more effective

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