Research interest areas that appear in the scientific literature include: Muscle protein synthesis and body composition changes in adults with GH deficiency Recovery from musculoskeletal injury given GHs role in tissue repair Sleep quality, given GHs relationship to slow-wave sleep architecture Metabolic function, particularly lean mass preservation in aging populations Important caveat: most human studies are small, short-term, and conducted in specific populations (often GH-deficient patients)
Migliore E, Berti G, Galassi C, Pearce N, Forastiere F, et al: SIDRIA-2 Collaborative Group
Researchers have also looked into DSIPs neuroprotective potential using models of ischaemic injury
It is generally advised to take ALCAR on an empty stomach or between meals to maximize absorption, as taking it with a heavy mealparticularly one high in proteincan cause the compound to compete with other amino acids for intestinal transport
Comparison of Properties The Bioavailability Challenge The most important question you should ask about any supplement is: "Does my body actually absorb this?" Bioavailability refers to the amount of a nutrient that enters your bloodstream and becomes available for use by your cells
Thus, research should be expanded further to include studies on chronic fatigue states humans, before considering polyphenols for clinical use in patients with CFS