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Immunity 54 , 211224 (2021)

Sousa, L., Oliveira, M

Enrichment analysis then assesses whether specific COG/KOG functional categories are over-represented in a subset of proteins or differential gene sets relative to a background distribution, typically using hypergeometric tests or related statistical approaches

The peptides natural presence in human plasma declines significantly with age, correlating directly with age-related tissue degradation

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