This matters because many adults with low B12, whether from dietary restriction, aging, or conditions like pernicious anemia, cannot absorb enough B12 through food or oral supplements alone
Most research focuses on: Cosmetic appearance improvements Skin conditioning properties Laboratory and early-stage studies They are not medical treatments, and results depend on formulation, concentration, and product system
See below for important safety information
According to the National Institutes of Health, B12 deficiency can cause damage to the nervous system before a blood test indicates anything
Further, long-term use of acid-reducing drugs and the anti-diabetes drug metformin and repeated exposure to nitrous oxide have been implicated in vitamin B 12 deficiency (see Drug interactions)
Research Focus : Safety & Metabolism (Non-Clinical) Title : Safety and Metabolism of AOD9604, a Novel Nutraceutical Ingredient for Improved Metabolic Health (J Endocrinol Metab, Vol 4, No 3, June 2014) Authors : Margret I