But the medical reality is far less dramatic
While known for weight loss, Jensen says the benefits extend beyond the scale
Can You Take the Skinny Shot and Ozempic Together
Traditional Medical Weight Loss Clinics Some Jacksonville weight loss clinics offer GLP-1 but embed it within expensive comprehensive programs requiring upfront fees of $1,000-$3,000+, mandatory purchases of meal replacements or supplements, and long-term contracts with limited flexibility
| Category | Zepbound | Mounjaro | |-----------------------------------|------------------------------------------------|------------------------------------------------| | FDA Approval Indication | Obesity and overweight management (with comorbidities) | Type 2 diabetes management | | Year of FDA Approval | 2023 | 2022 | | Active Ingredient | Tirzepatide | Tirzepatide | | Dose Range | 2.5 mg to 15 mg once weekly | 2.5 mg to 15 mg once weekly | | Primary Clinical Purpose | Weight loss | Blood sugar control | | GLP-1/GIP Activity | Dual agonist (GLP-1 + GIP) | Dual agonist (GLP-1 + GIP) | | Average Weight Loss (in trials) | Up to 22.5% of body weight in SURMOUNT-1 study | Up to 15% of body weight in SURPASS studies | | Insulin Sensitivity Impact | Improves insulin sensitivity in patients with obesity | Improves insulin sensitivity in type 2 diabetes patients | | Delivery Method | Single-use auto-injector pen, subcutaneous injection | Single-use auto-injector pen, subcutaneous injection | | Dosing Frequency | Once weekly | Once weekly | | Manufacturer | Eli Lilly | Eli Lilly | | Common Side Effects | Nausea, vomiting, diarrhea, constipation, decreased appetite | Nausea, vomiting, diarrhea, constipation, decreased appetite | | Insurance Coverage | Variable
Cells were lysed in KRBH + 0.1% Triton X-100 and sonicated, while islets were lysed in acidic ethanol (75% ethanol, 15 mM HCl)
