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Mice given extra GLP-1 (via gene therapy or a GLP-1 agonist drug) developed more oxidative, fatigue-resistant muscle fibers (more Type I fibers), built up greater muscle glycogen stores, and increased mitochondrial biogenesis changes that enhanced their endurance performance (1)

Older adults, especially those 65 and over, also face barriers, as Medicare does not currently cover GLP-1 medications for obesity

A summary of the main factors influencing GLP-1 secretion is shown in the image below (Huber et al, 2024)

d) Microneedling with Serums This technique uses micro-needles to create tiny punctures in the skin, enhancing the absorption of brightening serums like Vitamin C, niacinamide, or tranexamic acid

It may also shift melanin synthesis toward lighter pigments, resulting in a brighter-looking complexion

As a physician dedicated to regenerative and musculoskeletal medicine, I deeply value scientific innovation and remain enthusiastic about future breakthroughs in this area