Core Thesis : Easing supply constraints and rising market penetration should translate into high-margin revenue acceleration and reinforce Lillys leadership in the obesity market
In the context of glutathione deficiency or impaired GST activity, this conjugation pathway is compromised, leading to the intracellular accumulation of reactive species and an increased risk of macromolecular damage and cellular dysfunction
The main limitations are GI side effects: nausea, constipation, and slowed gastric emptying
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Husain M, Birkenfeld AL, Donsmark M, PIONEER 6 Investigators, et al
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