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Keep the pen cap on when not in use to protect from light and reduce contamination risk of the needle attachment site

Cover the skin as desired with a thin layer 1 to 3 times daily

Nassir, F., Rector, R

When activated, the mast cells in the skin release mediators (histamines, tryptase, TNF-alpha, CXCL9, etc.) that cause inflammation, flushing, itching, or burning.[ref] Related article: Rosacea, underlying causes, genetic susceptibility Dermatographism and mast cell activation syndrome: In a survey of mast cell activation syndrome, dermatographism was found in 89% of the patients.[ref] Dermatographism is when you get welts or raised red lines when you scratch your skin lightly

The thigh has some practical advantages

One factor with any peptide is immunogenicity, which is an unintended immune response to the therapy