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Drug-induced liver injury (DILI) refers to liver injury caused by ingestion of prescription drugs, over-the-counter medications, herbal products, or dietary supplements

The tissue-specific, context-dependent nature of palmatine s effect on cell death, being pro-apoptotic in cancer cells and anti-apoptotic in hepatocytes, further underscores its role as a fine-tuner of apoptotic signaling networks 85

When reconstituted with bacteriostatic water and stored properly in a refrigerator (around 2-8C or 36-46F), a peptide solution is typically stable for research purposes for up to 4 to 6 weeks

As in OVX or aged rats, mitochondrial dysfunction and overproduction of ROS are two common characteristics of AD animal models and patients with AD (Starkov, 2008)