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Description

Type 1 and type 2 deiodinases catalyse the conversion of thyroxine (T4) into the metabolically active triiodothyronine (T3), whilst type 3 deiodinase inactivates both hormones [2]

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113 , E538E547 (2016)

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These models allow researchers to zero in on and study the target TSH receptor, thyroid follicular cells, and the feedback mechanisms along the HPT axis to gain insight into how dysregulated thyroid hormone signaling contributes to metabolic disturbances associated with hyperthyroidism Kohn et al

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Thomma BP, Cammue BP, Thevissen K

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[DOI] [PMC free article] [PubMed] [Google Scholar] 36.Alharbi S.H

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