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have new or worsening symptoms of congestive heart failure such as shortness of breath or increased fluid or swelling of the legs

"Zepbound slows gastric emptying and alters gut hormone signaling, which can change how food moves through the intestines," says Supriya Rao, MD , a quadruple board-certified provider in internal medicine, gastroenterology, obesity, and lifestyle medicine

Coverage rules, eligible provider types, and reimbursed services vary by state

Steady-state plasma concentrations land after about 4-5 half-lives, or roughly 4 weeks at each dose step

Smita Ramanadham previously told the Daily Mail