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Symptomatic NCM occurs in approximately 4% of patients with a high-risk CMN, with onset of clinical manifestations (eg, hydrocephalus and seizures) at a median age of 2 years and a poor prognosis even in the absence of malignancy
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Cost: The average retail price for Byetta is $1019.28 per month without insurance
The human GPX3 gene consists of five exons in the 5q32 region of chromosome 5, it is 10 kb in length and it encodes a 23-kDa protein that forms a homotetramer (14)
To make monthly dosing possible, Pfizer and Amgen had to engineer new drugs that remain active in the body far longer