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The increase in older people, at least in part, relates to increased life span, increased weight (obesity is associated with gout) and increased use of diuretics

doi: 10.1073/pnas.84.24.8879

At 6 mg/mL, 3 mg equals 0.5 mL, or 50 units

This mechanistic debate has been addressed in subsequent literature as reflecting differences in cell culture conditions, peptide batches, and choice of IGF-1 axis inhibitors and does not invalidate the substantial positive evidence base but represents an important research context requiring careful experimental design

The peptides effects are more predictable and less subject to personal variation in pituitary function or response to growth hormone secretagogues

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