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The results of previous studies show that APOL1 risk variants can create a pore in a lipid layer that only allows the passage of Na + and K + ions (223, 224)

They are not FDA-approved for type 1 diabetes

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Digoxin is used to treat atrial fibrillation, and atorvastatin is a lipid-lowering drug used to treat patients with high cholesterol and to lower the risk of CV disease in patients who are at an increased risk of heart disease [5, 6]

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21 A direct comparison (SURMOUNT-5, NCT05822830) has found tirzepatide to be superior to semaglutide in respect to 72-week reductions in weight and waist circumference ( Figure 1 )