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323325 Specifically, activation of GLP-1R leads to an increase in cAMP levels, which in turn activates PKA, a widely regulating enzyme of cellular functions, capable of phosphorylating a variety of target proteins, thereby initiating the PKA/CREB signaling pathway

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Glutathione is the essential co-factor or the product of several oxido-reductases, which link the NAD(P)H pool (that is produced by metabolic carbohydrate conversion to carbon dioxide), to the reduction of ROS generated by the electron flux of oxidative phosphorylation