This triple mechanism of action distinguishes it from existing agents such as semaglutide (a GLP-1 receptor agonist) and tirzepatide (a dual GLP-1/GIP receptor agonist), and is thought to produce more pronounced effects on weight reduction and metabolic control
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Ultimately, the best care for NDDs might involve combining both: for example, using a disease-modifying drug to reduce protein aggregation in the brain and a microbiome therapy to reduce inflammation and enhance resilience
One such adaptation she and her colleagues have been studying is an increase in the amount of the enzyme glutamine synthetase, which makes glutamine from other starting materials, namely glucose
Neuman, A