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Consequently, although GLP-1RAs hold considerable promise for RA treatment, their clinical translation is constrained by both unresolved mechanistic questions and systemic administration failing to achieve therapeutic intra-articular concentrations constrain their application
The optic nerve transmits visual information from the eye to the brain, and damage to this structure can result in sudden vision loss
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The same phenomenon was evident in those receiving other glucose-lowering medications (such as insulin or SGLT-2 inhibitors) as part of the standard of care (82, 85)