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In people with both type 2 diabetes and obesity, an indirect comparison drawing on the separate SURMOUNT-2 (NCT04657003) and STEP 2 (NCT03552757) trials, rather than a single head-to-head study, reported weight reduction of up to 15.7% with tirzepatide and 10.6% with semaglutide 2.4 mg

This long half-life provides the widest flexibility window for early dosing

If youre struggling with side effects, youre not aloneand you never need to make dosing changes on your own

Its very relaxing and the office is very clean

This is challenging when your appetite is suppressed

[DOI] [PMC free article] [PubMed] [Google Scholar] 101.Darpo B, Zhou M, Matthews J, Zhi H, Young MA, Perry C, Reinhardt RR