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Niacinamide helps lighten dark spots and hyperpigmentation gradually over time, while vitamin C works more directly on reducing existing pigmentation and preventing new spots from forming

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[DOI] [PubMed] [Google Scholar] Elrick H, Stimmler L, Hlad CJ, Jr, Arai Y

Product Dosing, Composition, and Administration A powder blend of N-acetylcysteine (NAC) and glycine was tested at three different daily doses: 2.4 g of actives (1.2 g NAC + 1.2 g glycine), 4.8 g of actives (2.4 g NAC + 2.4 g glycine), and 7.2 g of actives (3.6 g NAC + 3.6 g glycine) per day

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however, these treatments do not reduce the size of uterine fibroids