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For instance, a study shows that after topical application of L-carnitine alone, the concentration in the local tissue is only 1/10 to 1/5 of that after oral administration, and it cannot significantly increase the proportion of fatty acid oxidation

This works by inhibiting tyrosinase, an enzyme involved in the production of melanin (the pigment for both skin and hair)

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on the other hand, the phosphorylation of NF-B-p65 can inhibit ER stress-mediated IEC ferroptosis to mitigate UC (141)

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[DOI] [PubMed] [Google Scholar] 5.Drucker DJ, Buse JB, Taylor K, Kendall DM, Trautmann M, Zhuang D, et al