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At 12 h, catalase activity was also upregulated and significantly higher in proline group and differences of total glutathione and reduced glutathione level between both groups was the most significant with levels two times higher in proline group

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N-acetyl-L-cysteine (NAC), low-molecular-weight dextran sulfate (LMW-DS), fondaparinux, and bivalirudin inhibit the coagulation system, while PMX53, ripasudil, gadolinium chloride (GdCl 3 ), and glycine inhibit innate immune system, thereby alleviating hepatocyte clearance

Blood sugar control remains the single most important modifiable factor for diabetic neuropathy