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Future research should prioritize long-term safety assessments, efficacy evaluations in specific populations, exploration of novel indications (eg, metabolic-associated fatty liver disease and obstructive sleep apnea), and mechanistic studies to enhance the therapeutic utility of these agents in metabolic and related diseases (See Figure 7)

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Acute Hemolytic Anemia With most G6PD variants, hemolysis occurs only after exposure to oxidant stresses

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