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Quantitative weight loss was only reported for the cohort receiving 0.01 mg/kg/24 h via SC infusion for 28 days, indicating an average weight reduction of 3 kg (-3.1%) compared to baseline and nearly 4 kg (-4.06%) compared to placebo as shown by ( Table 2 )

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Other GLP-1 Medications: Dulaglutide (Trulicity): Once-weekly GLP-1 agonist FDA-approved for diabetes only Not typically prescribed for weight loss Modest weight loss (3-5 kg average) Exenatide (Byetta, Bydureon): Older GLP-1 agonist Daily or weekly depending on formulation Less effective than newer options Rarely used now Oral Semaglutide (Rybelsus): Daily tablet form of semaglutide Much less effective than injectable (3-5% weight loss) Strict dosing requirements (empty stomach, wait 30 minutes) Not recommended for weight loss Side-by-Side Comparison: Which GLP-1 Should You Choose

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