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GLP-1RAs, which increase satiety and reduce hunger and increasing satiety could exacerbate dietary restriction (i.e., physiological undereating) and dietary restraint (i.e., the cognitive effort to reduce food intake) by encouraging the adoption of extreme and rigid dietary rules (see Figure 1)

Rolff, M., Schottenheim, J., Decker, H

Long-term Considerations Some patients worry about semaglutide withdrawal symptoms diarrhea when considering long-term treatment

But the early weeks are often less about visible weight loss than about how your body handles the drug

EASL Clinical Practice Guidelines on the prevention, diagnosis and treatment of gallstones