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However, tirzepatide can cause dehydration through gastrointestinal fluid losses, particularly if patients experience significant nausea, vomiting, or diarrhea

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Transdermal delivery bypasses the GI tract, which could alter both the effective dose range and the side effect profile

So, if we go back to our 200-pound person, that could mean a total loss of 30 to 32 pounds over that longer period

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