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Adult tobacco smoking also comprises a massive proportion of all healthcare spending on inpatient care, non-inpatient care, and prescription medications

Currently, mitophagy signaling pathways mainly include the PINK1 (PTEN induced putative kinase 1)/Parkin (E3 ubiquitin ligases) signaling pathway, BNIP3 (BCL2/adenovirus E1B 19 kDa interacting protein 3-like) /NIX / (Nip3-like protein X) signaling pathway and FUNDC1 (FUN14 domain containing 1) signaling pathway (Fig

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