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AM has received support from Italian Ministry of Health, Ricerca Corrente Program, to the IRCCS Istituto Ortopedico Galeazzi

This effect is completely inhibited in the presence of a P2X7 purinergic receptor inhibitor (BBG), but not in the presence of glutamatergic ionotropic NMDA and non-NMDA antagonists (MK-801 + DNQX)

Transgenic Res

CPR: Cytochrome P450 reductase

KISS: Korean Studies Information Service System, NDSL = National Discovery for Science Leaders, OASIS = Oriental Medicine Advanced Searching Integrated System, RCTs = randomized controlled trials, ROBANS = risk of bias assessment tool for non-randomized studies

This process, known as biotransformation, converts lipophilic substances to hydrophilic ones for subsequent elimination