It is thought that the vasoconstrictive effect of phosphodiesterase inhibitors may decrease blood flow to the optic nerve, especially in patients with a low cup to disc ratio
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Feng T, Zhao X, Gu P, Yang W, Wang C, Guo Q, et al
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FIGURE 4 3.7 Histopathological changes Microscopic analysis of the renal cortex of the rats in the control group exhibited a normal renal architecture, which was characterized by intact glomeruli and tubules (lesion score: 0) (Figure 5A)
A lead time of 16 months could be a life-changing for patients and their families