Van Der Velpen et al., 2019
And importantly, clinicians should remain open to considering rare diagnoses like ROHHAD when the phenotype includes hypoventilation, autonomic dysregulation, or extreme hyperphagia. Perhaps one of the most exciting takeaways is that this patients hyperphagia improved markedly (and likewise quickly worsened during medication interruptions), suggesting that some of her hyperphagia was being modulated by GLP-1 RA therapy
In a preliminary study that included seven women with a history of biliary problems during pregnancy, taking 800 mg oral SAMe daily for two weeks resulted in decreased cholesterol saturation in the bile (Frezza 1988)
In rodents, GLP-1 has been shown to increase the biosynthesis of glucose transporter 2 (GLUT-2) and glucokinase [29]
Absorbance was measured at 450 nm and 37 C in a CLARIOstar Plus Microplate (BMG LABTECH) using kinetic mode with measurements every 1 min for 45 min
And every year, we see several patients in the emergency room with damage from Halloween contact lenses. Steven Reed, an optometrist and the president of the American Optometric Association, expresses similar concern: Allergic reactions or bacterial eye infections from contaminated, poorly fitted decorative lenses can occur rapidly, causing a painful corneal ulcer or even significant damage to the eyes ability to function, which could lead to irreversible sight loss. Experts also advise against potentially dangerous invasive procedures and surgeries performed to manipulate eye color, like keratopigmentation, which involves inserting pigment into the cornea
