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Weight of evidence: Overall evidence is Moderate : pediatric trials show lipid-peroxidation reduction and improved antioxidant status, with mixed behavioral effects

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In a frequently cited study, GHK-Cu introduced by repeated injection into stainless-steel wire-mesh wound chambers implanted subcutaneously in rats produced a concentration-dependent increase in the accumulation of connective tissue, raising dry weight, DNA, total protein, collagen, and glycosaminoglycan content at the repair site, while an inactive control tripeptide did not